Hové, Carmen, Trumble, Benjamin C., Anderson, Amy, Stieglitz, Jonathan, Kaplan, Hillard, Gurven, Michael and Blackwell, Aaron D. (2020) Immune function during pregnancy varies between ecologically distinct populations. Evolution, Medicine, and Public Health (1). pp. 114-128.

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Official URL : http://iast.fr/pub/124727
Identification Number : 10.1093/emph/eoaa022


Background and objectives: Among placental mammals, females undergo immunological shifts during pregnancy to accommodate the fetus (i.e. fetal tolerance). Fetal tolerance has primarily been characterized within post-industrial populations experiencing evolutionarily novel conditions (e.g. reduced pathogen exposure), which may shape maternal response to fetal antigens. This study investigates how ecological conditions affect maternal immune status during pregnancy by comparing the direction and magnitude of immunological changes associated with each trimester among the Tsimane (a subsistence population subjected to high pathogen load) and women in the USA.

Item Type: Article
Language: English
Date: July 2020
Refereed: Yes
Divisions: TSE-R (Toulouse)
Site: UT1
Date Deposited: 29 Sep 2020 09:14
Last Modified: 08 Jun 2023 11:31
OAI Identifier: oai:tse-fr.eu:124727
URI: https://publications.ut-capitole.fr/id/eprint/41804
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