Banos, Arnaud, Corson, Nathalie, Gaudou, Benoit, Laperrière, Vincent and Rey Coyrehourcq, Sébastien (2015) The Importance of Being Hybrid for Spatial Epidemic Models: A Multi-Scale Approach. Systems, 3 (4). pp. 309-329.

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This work addresses the spread of a disease within an urban system, defined as a network of interconnected cities. The first step consists of comparing two different approaches: a macroscopic one, based on a system of coupled Ordinary Differential Equations (ODE) Susceptible-Infected-Recovered (SIR) systems exploiting populations on nodes and flows on edges (so-called metapopulational model), and a hybrid one, coupling ODE SIR systems on nodes and agents traveling on edges. Under homogeneous conditions (mean field approximation), this comparison leads to similar results on the outputs on which we focus (the maximum intensity of the epidemic, its duration and the time of the epidemic peak). However, when it comes to setting up epidemic control strategies, results rapidly diverge between the two approaches, and it appears that the full macroscopic model is not completely adapted to these questions. In this paper, we focus on some control strategies, which are quarantine, avoidance and risk culture, to explore the differences, advantages and disadvantages of the two models and discuss the importance of being hybrid when modeling and simulating epidemic spread at the level of a whole urban system.

Item Type: Article
Language: English
Date: 2015
Refereed: Yes
Uncontrolled Keywords: ODE - Network - Metapopulation - Model coupling - Mobility - Disease spread - City systems - Agent-based modeling
Divisions: Institut de Recherche en Informatique de Toulouse
Site: UT1
Date Deposited: 12 Mar 2019 09:11
Last Modified: 02 Apr 2021 15:59
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