RT Journal Article
SR 00
ID 10.1007/s44250-025-00196-9
A1 Bardey, David
A1 De Donder, Philippe
A1 Zaporozhets, Vera
T1 The Health Technology Assessment Approach of the Economic Value of Diagnostic Tests : A Literature Review
JF Discover Health Systems
YR 2025
FD 2025-03-23
VO Vol. 4
IS N° 26
K1 Genetic tests
K1 Innovative tests
K1 Companion tests
K1 Health Technology Assessment (HTA)
K1 Personalized medicine
K1 Receiver-operator (ROC) curve
K1 Incremental cost-effectiveness ration (ICER)
AB We review the medico-economic literature assessing the economic value of diagnostic and prognostic tests, with a focus on innovative and, more specifically, companion tests. Our analysis begins with a summary of systematic reviews that provide a descriptive synthesis of existing findings rather than conducting quantitative meta-analyses. These reviews reveal no consistent evidence that such tests outperform traditional approaches, such as pharmaceutical interventions. However, the cost-effectiveness of these tests, often measured in cost per QALY (Quality-Adjusted Life Year) gained, exhibits considerable heterogeneity. Notably, some genetic testing procedures may demonstrate superior performance compared to non-genetic alternatives. We then examine the economic implications of imperfect test features, exploring strategies to optimize their accuracy levels and integrating these considerations into the assessment of their economic value. Lastly, we review recent methodological and empirical studies employing these approaches, highlighting advancements in evaluating the economic impact of diagnostic and prognostic tests.
PB Springer Nature Switzerland AG
SN 2731-7501
LK https://publications.ut-capitole.fr/id/eprint/50769/
UL http://tse-fr.eu/pub/130496