?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.relation=https%3A%2F%2Fpublications.ut-capitole.fr%2Fid%2Feprint%2F48675%2F&rft.title=The+Health+Technology+Assessment+Approach+of+the+Economic+Value+of+Diagnostic+Tests+-+A+Literature+Review&rft.creator=Bardey%2C+David&rft.creator=De+Donder%2C+Philippe&rft.creator=Zaporozhets%2C+Vera&rft.subject=B-+ECONOMIE+ET+FINANCE&rft.description=We+review+the+medico-economic+literature+assessing+the+economic+value+of+diagnostic+tests.+We+first+present+the+health+technology+assessment+methods%2C+as+applied+to+generic+health+interventions.+We+then+define+our+object+of+study%2C+diagnostic+and+prognostic+tests%2C+and+relate+them+to+various+definitions+of+personalized+medicine.+We+then+review+the+empirical+assessments+of+diagnostic+tests+related+to+personalized+medicine+andof+companion+tests.+We+summarize+systematic+reviews+which+are+not+performing+quantitative+meta-analyses%2C+but+rather+provide+a+descriptive+synthesis+of+the+results+reviewed.+We+find+no+evidence+that+such+tests+perform+better+than+more+traditional+approaches%2C+such+as+pharmaceutical+interventions.+At+the+same+time%2C+there+is+a+lot+of+heterogeneity+in+the+cost+per+QALY+(Quality-Adjusted+Life+Year)+gained%2C+so+that+some+genetic+testing+procedures+may+perform+better+than+non-genetic+ones.+Finally%2C+we+focus+on+imperfect+tests+and+show+how+to+optimize%2C+from+an+economic+perspective%2C+their+accuracy+levels%2C+and+how+to+take+accuracy+levels+into+considerations+when+assessing+their+economic+value.&rft.publisher=TSE+Working+Paper&rft.date=2024-02&rft.type=Monograph&rft.type=NonPeerReviewed&rft.format=text&rft.language=en&rft.identifier=https%3A%2F%2Fpublications.ut-capitole.fr%2Fid%2Feprint%2F48675%2F1%2Fwp_tse_1508.pdf&rft.identifier=++Bardey%2C+David+%3Chttps%3A%2F%2Fwww.idref.fr%2F06064754X%3E%2C+De+Donder%2C+Philippe+%3Chttps%3A%2F%2Fwww.idref.fr%2F199756120%3E+and+Zaporozhets%2C+Vera+%3Chttps%3A%2F%2Fwww.idref.fr%2F241587085%3E++(2024)+The+Health+Technology+Assessment+Approach+of+the+Economic+Value+of+Diagnostic+Tests+-+A+Literature+Review.++TSE+Working+Paper%2C+n.+24-1508%2C+Toulouse+++++&rft.relation=http%3A%2F%2Ftse-fr.eu%2Fpub%2F129121&rft.language=en