?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.relation=https%3A%2F%2Fpublications.ut-capitole.fr%2Fid%2Feprint%2F46752%2F&rft.title=Optimal+Intertemporal+Curative+Drug+Expenses%3A+The+Case+of+Hepatitis+C+in+France&rft.creator=Dubois%2C+Pierre&rft.creator=Magnac%2C+Thierry&rft.subject=B-+ECONOMIE+ET+FINANCE&rft.description=We+study+intertemporal+trade-offs+that+health+authorities+(HAs)+face+when+considering+the+control+of+an+epidemy+using+innovative+curative+medical+treatments.+We+set+up+a+dynamically+controlled+Susceptibles-Infected-Recovered+(SIR)+model+for+an+epidemy+in+which+patients+can+be+asymptomatic%2C+and+we+analyze+in+a+simple+model%2C+the+optimality+conditions+of+the+sequence+of+cure+expenses+decided+by+HAs+at+the+onset+of+the+drug+innovation.+We+show+that+analytical+conclusions+are+ambiguous+because+of+their+dependence+on+parameter+values.+As+an+application%2C+we+focus+on+the+case-study+of+Hepatitis+C+whose+treatment+underwent+a+major+up-heaval+when+curative+drugs+were+introduced+in+2014.+We+calibrate+our+controlled+SIR+model+using+French+data+and+simulate+optimal+policies.+We+show+that+the+optimal+policy+entails+some+front+loading+of+the+intertemporal+budget+compared+to+fixed+annual+ones.+The+analysis+demonstrates+how+beneficial+the+intertemporal+budgeting+can+be+compared+to+non+forward+looking+constant+budget+allocation.&rft.publisher=TSE+Working+Paper&rft.date=2023-01&rft.type=Monograph&rft.type=NonPeerReviewed&rft.format=text&rft.language=en&rft.identifier=https%3A%2F%2Fpublications.ut-capitole.fr%2Fid%2Feprint%2F46752%2F1%2Fwp_tse_1402.pdf&rft.identifier=++Dubois%2C+Pierre+%3Chttps%3A%2F%2Fwww.idref.fr%2F172637546%3E+and+Magnac%2C+Thierry+%3Chttps%3A%2F%2Fwww.idref.fr%2F032900279%3E++(2023)+Optimal+Intertemporal+Curative+Drug+Expenses%3A+The+Case+of+Hepatitis+C+in+France.++TSE+Working+Paper%2C+n.+23-1402%2C+Toulouse+++++&rft.relation=http%3A%2F%2Ftse-fr.eu%2Fpub%2F127775&rft.language=en