eprintid: 41804 rev_number: 17 eprint_status: archive userid: 1482 importid: 105 dir: disk0/00/04/18/04 datestamp: 2020-09-29 09:14:56 lastmod: 2023-06-08 11:31:13 status_changed: 2023-06-08 11:31:03 type: article metadata_visibility: show creators_name: Hové, Carmen creators_name: Trumble, Benjamin C. creators_name: Anderson, Amy creators_name: Stieglitz, Jonathan creators_name: Kaplan, Hillard creators_name: Gurven, Michael creators_name: Blackwell, Aaron D. creators_idrefppn: 241587034 creators_affiliation: Institute for Advanced Study in Toulouse title: Immune function during pregnancy varies between ecologically distinct populations ispublished: pub subjects: subjects_ECO abstract: Background and objectives: Among placental mammals, females undergo immunological shifts during pregnancy to accommodate the fetus (i.e. fetal tolerance). Fetal tolerance has primarily been characterized within post-industrial populations experiencing evolutionarily novel conditions (e.g. reduced pathogen exposure), which may shape maternal response to fetal antigens. This study investigates how ecological conditions affect maternal immune status during pregnancy by comparing the direction and magnitude of immunological changes associated with each trimester among the Tsimane (a subsistence population subjected to high pathogen load) and women in the USA. date: 2020-07 date_type: published publisher: Oxford academic id_number: 10.1093/emph/eoaa022 official_url: http://iast.fr/pub/124727 faculty: tse divisions: tse language: en has_fulltext: FALSE doi: 10.1093/emph/eoaa022 view_date_year: 2020 full_text_status: none publication: Evolution, Medicine, and Public Health number: 1 pagerange: 114-128 refereed: TRUE issn: 2050-6201 oai_identifier: oai:tse-fr.eu:124727 harvester_local_overwrite: publish_to_hal harvester_local_overwrite: faculty harvester_local_overwrite: pending harvester_local_overwrite: note harvester_local_overwrite: creators_affiliation harvester_local_overwrite: publisher harvester_local_overwrite: hal_id harvester_local_overwrite: hal_version harvester_local_overwrite: hal_url harvester_local_overwrite: hal_passwd harvester_local_overwrite: doi harvester_local_overwrite: id_number harvester_local_overwrite: creators_idrefppn oai_lastmod: 2023-05-26T11:43:11Z oai_set: tse site: ut1 publish_to_hal: TRUE hal_id: hal-02952113 hal_passwd: b?rmpsk hal_version: 1 hal_url: https://hal.archives-ouvertes.fr/hal-02952113 citation: Hové, Carmen, Trumble, Benjamin C., Anderson, Amy, Stieglitz, Jonathan , Kaplan, Hillard, Gurven, Michael and Blackwell, Aaron D. (2020) Immune function during pregnancy varies between ecologically distinct populations. Evolution, Medicine, and Public Health (1). pp. 114-128.