TY  - JOUR
ID  - publications41804
UR  - http://iast.fr/pub/124727
IS  - 1
A1  - Hové, Carmen
A1  - Trumble, Benjamin C.
A1  - Anderson, Amy
A1  - Stieglitz, Jonathan
A1  - Kaplan, Hillard
A1  - Gurven, Michael
A1  - Blackwell, Aaron D.
Y1  - 2020/07//
N2  - Background and objectives: Among placental mammals, females undergo immunological shifts during pregnancy to accommodate the fetus (i.e. fetal tolerance). Fetal tolerance has primarily been characterized within post-industrial populations experiencing evolutionarily novel conditions (e.g. reduced pathogen exposure), which may shape maternal response to fetal antigens. This study investigates how ecological conditions affect maternal immune status during pregnancy by comparing the direction and magnitude of immunological changes associated with each trimester among the Tsimane (a subsistence population subjected to high pathogen load) and women in the USA.
PB  - Oxford academic
JF  - Evolution, Medicine, and Public Health
SN  - 2050-6201
TI  - Immune function during pregnancy varies between ecologically distinct populations
SP  - 114
AV  - none
EP  - 128
ER  -