@inproceedings{publications29730, booktitle = {the Fourteenth International Conference on the Synthesis and Simulation of Living Systems - ALIFE 2014}, title = {Self-organization of Symbiotic Multicellular Structures}, author = {Jean Disset and Sylvain Cussat-Blanc and Yves Duthen}, publisher = {The MIT Press}, year = {2014}, pages = {541--548}, keywords = {Artificial creatures - Cellular physic system - Intercellular adhesion dynamics - Cell cycle - Multicellular organism}, url = {https://publications.ut-capitole.fr/id/eprint/29730/}, abstract = {This paper presents a new model for the development of artificial creatures from a single cell. The model aims at providing a more biologically plausible abstraction of the morphogenesis and the specialization process, which the organogenesis follows. It is built upon three main elements: a cellular physics system that simulates division and intercellular adhesion dynamics, a simplified cell cycle offering to the cells the possibility to select actions such as division, quiescence, differentiation or apoptosis and, finally, a cell specialization mechanism quantifying the ability to perform different functions. An evolved artificial gene regulatory network is employed as a cell controller. As a proof-of-concept, we present two experiments where the morphology of a multicellular organism is guided by cell weaknesses and efficiency at performing different functions under environmental stress.} }