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Infect Immun. 1989 Oct; 57(10): 3237–3239.
PMCID: PMC260797
PMID: 2506134

Spontaneous mutation results in loss of the cytadhesin (P1) of Mycoplasma pneumoniae.

Abstract

The cytadhesin (P1) structural gene of a spontaneous mutant of Mycoplasma pneumoniae which displayed a P1-negative phenotype was analyzed. An extra adenine was discovered in a stretch of normally seven adenines near the N-terminal region of the mutant P1 structural gene. The frameshift mutation resulted in the early termination of protein translation. Possible causes of the mutation are discussed.

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Selected References

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