Impacts of Patent Expiry of Pharmaceutical Treatments in Eight OECD Countries, 2004-2010

Berndt, Ernst R. and Dubois, Pierre (2016) Impacts of Patent Expiry of Pharmaceutical Treatments in Eight OECD Countries, 2004-2010. International Journal of the Economics of Business, vol. 23 (n° 2). pp. 125-147.

This is the latest version of this item.

Download (840kB) | Preview
Official URL:


Variability in regulatory frameworks, industrial policy, physician/pharmacy autonomy, brand/generic distinctions, and the practice of medicine contribute to ambiguous interpretations of cross-country pharmaceutical cost comparisons. Here, we report cross-country comparisons that: (i) focus on ten therapeutic classes experiencing patent expiration and loss of exclusivity 2004–2010 in eight industrialized countries; (ii) convert revenues and unit sales to cost per day of treatment and number patient days treated using the World Health Organization’s Defined Daily Dosage metrics; (iii) compare patterns in costs per day of treatment with price index measures based on average price per day of treatment for each molecule computed over all molecule versions; (iv) utilizing econometric methods, model and quantify various factors affecting variations in daily treatment price indexes such as national regulatory and reimbursement policy changes, physician/pharmacy autonomy, and other factors; and (v) simulate changes in expenditures by country and therapeutic class had counterfactual policies been implemented.

Item Type: Article
Language: English
Date: May 2016
Refereed: Yes
Uncontrolled Keywords: Cross-Country Comparisons, Pharmaceutical Costs, Generic Drugs
JEL codes: D4 - Market Structure and Pricing
I11 - Analysis of Health Care Markets
I18 - Government Policy; Regulation; Public Health
L11 - Production, Pricing, and Market Structure; Size Distribution of Firms
L65 - Chemicals; Rubber; Drugs; Biotechnology
O34 - Intellectual Property Rights - National and International Issues
Divisions: TSE-R (Toulouse)
Site: UT1
Date Deposited: 19 Apr 2016 13:42
Last Modified: 07 Mar 2018 13:23

Available Versions of this Item

Actions (login required)

View Item View Item


Downloads per month over past year